Jim Woodgett

نویسنده

  • Jim Woodgett
چکیده

Jim Woodgett was born in rural Leicestershire, England and now makes his home in Toronto, Canada. He earned his PhD under the mentorship of Sir Philip Cohen in Dundee (1984) and completed post-doctoral studies with Tony Hunter at the Salk Institute (1987). He is currently Director of Research at the Samuel Lunenfeld Research Institute, where his laboratory studies the role of abrogated signal transduction processes in human diseases such as breast and colon cancer and diabetes. His primary contributions relate to the characterization of the biological role of protein kinases such as GSK-3, protein kinase B/Akt and stress-activated protein kinases.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Narration in Joseph Conrad's Lord Jim: A Postcolonial Reading

This study is an attempt at a colonial and postcolonial reading of Joseph Conrad’s Lord Jim. It is specifically focused on the narrative strategies used in the novel. In other words, it investigates the connection between the narrative strategy and a possible tone of imperialism in Conrad’s novel. For the introduction, a brief review of Conrad’s manner of writing and his peculiar ambiguity is p...

متن کامل

The Introductory Essay: Richard Wright's Covert Challenging of Jim Crowism and Uncle Tomism

Richard Wright’s introductory essay to his collection of short stories Uncle Tom's Children describes hidden forms of resistance against Jim Crowism and Uncle Tomism. The essay entitled The Ethics of Living Jim Crow: An Autobiographical Sketch relates Wright’s daily confrontations with Jim Crowism with a particular emphasis on his evasive actions, and his covert activities, such as silence, pla...

متن کامل

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

Canonical Wnt/beta-catenin signaling has central roles in development and diseases, and is initiated by the action of the frizzled (Fz) receptor, its coreceptor LDL receptor-related protein 6 (Lrp6), and the cytoplasmic dishevelled (Dvl) protein. The functional relationships among Fz, Lrp6 and Dvl have long been enigmatic. We demonstrated previously that Wnt-induced Lrp6 phosphorylation via gly...

متن کامل

Regulation of transcription factor function by proteolysis.

67 Kyriakis, J. M. et al. (1996) Nature (London) 380, 75-79 Zanke, B. W., Boudreau, K., Rubie, E., Winnett, E., Tibbles, L. A., Zon, L., Kyriakis, J., Liu, F. F. and Woodgett, J. R. (1996) Curr. Biol. 6, 606-613 McCarthy, S. A., Samuels, M. L., Pritchard, C. A., Abraham, J. A. and McMahon, M. (1995) Genes Dev. 9, 1953-1964 68 Nishima, H., Fischer, K. D., Radvanyi, L., Shahinian, A., Hakem, R., ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Current Biology

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2007